4th International Conference on Enzymology & Molecular Biology May 10-11, 2019 | Radisson Hotel Narita | Tokyo, Japan

Molecular enzymology is that branch of biochemistry which encircles or deals with the functional as well as the structural characteristics of the enzymes within a molecular level. Enzymes are globular proteins which play a very important role as a catalyst for any type of biochemical reactions. 

Clinical enzymology deals with the measurement of enzyme activity for the diagnosis and treatment of diseases. In general, most of the enzymes are present in cells at much higher concentrations than that in plasma. Measurement of these levels in plasma indicates whether their tissue of origin is damaged causing to the release of intracellular components into the blood.

Enzymes are the group of proteins which process cellular metabolism. They can affect a reaction either by catalysing or they can be used to reverse the reactions in bio-chemical pathways. Though enzymes have complex enzymatic structures, they undergo many changes which is very important for reactions and so enzyme structure is very much essential.

Enzymes are the vital activators in life processes, likewise in the soil they are known to play a substantial role in maintaining soil health and its environment. Soil enzymes are critically important to the functioning of the soil. The enzymatic activity in the soil is mainly of microbial origin, being derived from intracellular, cell-associated or free enzymes.Healthy soils are essential for the integrity of terrestrial ecosystems to remain intact or to recover from disturbances, such as drought, climate change, pest infestation, pollution, and human exploitation including agriculture.

Enzyme kinetics deals with the study of the chemical reactions that are catalyzed mainly by the enzymes. In enzyme kinetics, the rates of the reaction are measured and the effects of varying the conditions of the reaction are studied.

Enzymes are the macromolecular and micromolecular proteins in the drug design that act as drug targets for the diseases in the process of discovery of drugs as well as its development. Drug target is a nucleic acid or a protein whose activity can be modified by a drug itself. The drug target should be effective in the disease by relevant in vitro or in vivo models and analysis.

Proteomics is the large-scale study related to proteins, mainly their structures and functions. Proteins are the vital parts of all the living organisms, as they form the main components of the physiological metabolic pathways of the cells. The term proteomics was first coined in the year of 1997 to make an analogy with the term genomics, which again deals with the study of the genome.

Enzyme Toxicology is unremarkable, except the potential irritating effects usually associated with some proteases at high concentrations, and the allergic effects of enzymes. Like anything one is exposed to, the dose makes the poison; thus, with certain enzymes, a sufficient excess in exposure can lead to irritation. 

Most often this has been done in relation to enzymes to be used in foodstuffs and so exposure has been carried out via the oral route. 

Molecular simulations and modelling means altering the science of enzymology. Computational enzymology is a rapidly developing area, and is studying the theories of catalysis, challenging 'textbook' mechanisms, and also identifying the novel catalytic mechanisms. Also increasingly, modelling is contributing directly towards the experimental studies of the enzyme-catalysed reactions.

Enzymes are used nowadays in chemical industries and for some  industrial purposes where extremely specific catalysts are required for industrial uses. Enzymes in general are rare in number of reactions they have evolved to catalyse and also by the lack of stability in organic solvents and at very high temperatures. Enzymes are usually macromolecular and micromolecular protein molecules that manipulate the other molecules i.e., the enzymes substrates.

The nanomaterials possess ideal characteristics to equilibrate principal factors which determine biocatalysts efficiency, including specific surface area, mass transfer resistance and effective enzyme loading. This review presents the current scenario and techniques in enzyme immobilization. Some methods are used which are efficient to combine proteins/enzymes with nanoparticles. So far different matrices have been described in the literature to improve the performance of the immobilized enzymes.

In the presence of an enzyme, the reaction runs in the same direction as it would run without an enzyme, but just more quickly. The reaction rate is dependent on the activation energy which is needed to form the transition state which then transforms into products. Enzymes increase  the reaction rates by decreasing the transition state energy. First, binding forms an enzyme-substrate complex (ES) with low energy.

Food enzymology deals with all the aspects of the enzymology which are related to the food systems. The basic aspects of the food enzymology are the methods for measuring the enzyme activities; extraction of the enzymes from microbial, plant and animal systems; methods of purification of enzyme as well as its characterization.

The total cost of decreasing low-density lipoprotein generally includes the costs of physician services, case finding and monitoring, dietary and exercise modifications, medications, and also treating the side effects. The cost of treatment-related appointments follow-up or varies by type of provider, location, and practice setting.

Genomics is a domain of science that specialize in the structure, function, evolution, mapping, and redaction of genomes. An ordering is an organism's complete set of DNAs, as well as all of its genes. In distinction to biology, that refers to the study of individual genes and their roles in inheritance, genetics aims at the collective characterization and quantification of genes, that direct the assembly of proteins with the help of enzymes and traveler molecules. In turn, proteins compose body structures comparable to organs and tissues still as management chemical reactions and carry signals between cells.

The term genetic science  is currently redundant as a result of up to date genetics is totally molecular. biology isn't created of 2 sciences, one molecular and one non-molecular. Scientists typically speak and write of the applying of those techniques across a broad swath of medicine science. For them, genetic science is associate fact-finding approach that involves the applying of laboratory ways and analysis ways.